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Product Categories
Antibody Pair
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Product Name
TNF alpha Mouse mAb, capture
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Background
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
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Alternative Names
TNF; DIF; TNFA; TNFSF2; TNF-alpha
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Immunogen
A synthesized peptide derived from TNF
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Concentration
1 mg/ml
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Buffer System
Liquid in PBS containing 0.09% sodium azide as a preservative.
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Dilution Ratio
ELISA: 1/1000
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Molecular Weight
-
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Clonality
Monoclonal Antibody
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Gene Name
TNF
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Conjugation
Unconjugated
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Isotype
IgG1
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Host
Mouse
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Application
ELISA
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Purification
Affinity Purified
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Reactivity
Human
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Form
Liquid
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Clonality No.
7A8
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SwissProt ID
P01375
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Research Field
Immunology
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Gene ID
7124
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Modification
Unmodified