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Product Categories
Antibody Pair
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Product Name
alpha 1 Fetoprotein Mouse mAb, capture
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Background
Alpha-fetoprotein (AFP) is a 65 kDa glycoprotein found in the mammalian fetal liver, yolk sac, and GI tract. In normal adult cells, p53 binds to the repressor region of the AFP gene, thereby blocking transcription. Mutations in both p53 and β-catenin are associated with aberrant expression of AFP. Research studies have shown that elevated serum AFP levels are predictive of hepatocellular carcinoma .
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Alternative Names
FETA; HPAFP
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Immunogen
A synthesized peptide derived from AFP
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Concentration
1 mg/ml
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Buffer System
Liquid in PBS containing 0.09% sodium azide as a preservative.
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Dilution Ratio
ELISA: 1/1000
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Molecular Weight
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Clonality
Monoclonal Antibody
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Gene Name
AFP
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Conjugation
Unconjugated
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Isotype
IgG1
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Host
Mouse
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Application
ELISA
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Purification
Affinity Purified
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Reactivity
Human
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Form
Liquid
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Clonality No.
3C11
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SwissProt ID
P02771
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Research Field
Cancer
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Gene ID
174
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Modification
Unmodified