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Product Categories
Primary antibody
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Product Name
ALAS1 Rabbit mAb
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Background
5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells.
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Alternative Names
ALAS1; ALAS-H; 5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; ALAS3; ALASH
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Immunogen
A synthesized peptide derived from human Alas1
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 71 kDa; Observed MW: 71 kDa
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Gene Name
ALAS1
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Host
Rabbit
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Reactivity
Human
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Conjugation
Unconjugated
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Application
WB,ICC/IF
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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SwissProt ID
P13196
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Purification
Affinity Chromatography
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Clonality No.
R07-4E8
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Clonality
Monoclonal Antibody
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Isotype
IgG
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Form
Liquid
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Research Field
Cardiovascular
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Gene ID
211
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Modification
Unmodified