4E BP1 Rabbit pAb - Primary Antibodies - Chengdu Zhengneng Biotechnology Co., Ltd

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Cat.#： 382510

Alternative Names： EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I

Application： WB,IHC-P,FC,IP

Reactivity： Human

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Primary antibody
Product Name

4E BP1 Rabbit pAb
Background

Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation. Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity.
Alternative Names

EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I
Immunogen

A synthetic peptide of human eIF4EBP1
Buffer System

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20 FC: 1/50-1/100
Molecular Weight

Calculated MW: 13 kDa; Observed MW: 15-20 kDa
Clonality

Polyclonal Antibody
Gene Name

EIF4EBP1
Conjugation

Unconjugated
Isotype

IgG
Host

Rabbit
Application

WB,IHC-P,FC,IP
Purification

Affinity Purified
Reactivity

Human
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Form

Liquid
Clonality No.

-
SwissProt ID

Q13541
Research Field

Epigenetics and Nuclear Signaling
Gene ID

1978
Modification

Unmodified