BRAF Rabbit pAb - Primary Antibodies - Chengdu Zhengneng Biotechnology Co., Ltd

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Cat.#： 380931

Alternative Names： BRAF; BRAF1; RAFB1; Serine/threonine-protein kinase B-raf; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1

Application： WB,IHC-P,IP,FC

Reactivity： Human,Mouse,Rat

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Primary antibody
Product Name

BRAF Rabbit pAb
Background

Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Frequently mutated in thyroid cancers, skin melanomas and at lower frequency in a wide range of human cancers. An activating mutation, mimicking phosphorylation of the activation loop, is seen in 60% of malignant melanoma samples. Raf mutations are generally exclusive to Ras activating mutations.
Alternative Names

BRAF; BRAF1; RAFB1; Serine/threonine-protein kinase B-raf; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1
Immunogen

A synthesized peptide derived from human B Raf
Buffer System

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/50 FC: 1/50-1/100
Molecular Weight

Calculated MW: 84 kDa; Observed MW: 84 kDa
Clonality

Polyclonal Antibody
Gene Name

BRAF
Conjugation

Unconjugated
Isotype

IgG
Host

Rabbit
Application

WB,IHC-P,IP,FC
Purification

Affinity Chromatography
Reactivity

Human,Mouse,Rat
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Form

Liquid
Clonality No.

-
SwissProt ID

P15056
Research Field

Cell Biology
Gene ID

673
Modification

Unmodified