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Product Categories
Primary antibody
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Product Name
Phospho-AMPK alpha 2 (Thr172) Rabbit pAb
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Background
AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. AMPK is a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits, each of which is encoded by two or three distinct genes (α1, 2; β1, 2; γ1, 2, 3). The kinase is activated by an elevated AMP/ATP ratio due to cellular and environmental stress, such as heat shock, hypoxia, and ischemia.
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Alternative Names
PRKAA2; AMPK; AMPK2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase
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Immunogen
A synthesized peptide derived from human AMPK alpha
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 62 kDa; Observed MW: 62 kDa
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Clonality
Polyclonal Antibody
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Gene Name
PRKAA2
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Conjugation
Unconjugated
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Isotype
IgG
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Host
Rabbit
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Application
WB
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Purification
Affinity Chromatography
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Reactivity
Human,Mouse,Rat
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Form
Liquid
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Clonality No.
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SwissProt ID
P54646
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Research Field
Neuroscience
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Gene ID
5563
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Modification
Phosphorylated