Cat.#： 381683
Alternative Names： CD156b; ADAM17; CSVP; TACE
Application： WB,ICC/IF,IP,FC
Reactivity： Human,Mouse,Rat
Price：
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Quantity： - + （库存件）
Availability：3-4 working days Contact the local distributor
Doc. Data Sheet
Product Details
  • Product Categories
    Primary antibody
  • Product Name
    ADAM17 Rabbit pAb
  • Background
    TACE is responsible for the shedding of EGFR ligands such as amphiregulin and TNF-α. Some tumors have hyperactivated EGFR due to upregulated TNF-α production and upregulated TACE, making TACE a potential target for drug development. TACE activates Notch in a ligand-independent manner and has been shown to play a role in the development of the Drosophila nervous system.
  • Alternative Names
    CD156b; ADAM17; CSVP; TACE
  • Immunogen
    A synthesized peptide derived from human ADAM17
  • Buffer System
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Dilution Ratio
    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
  • Molecular Weight
    Calculated MW: 93 kDa; Observed MW: 100 kDa
  • Clonality
    Polyclonal Antibody
  • Gene Name
    ADAM17
  • Conjugation
    Unconjugated
  • Isotype
    IgG
  • Host
    Rabbit
  • Application
    WB,ICC/IF,IP,FC
  • Purification
    Affinity Chromatography
  • Reactivity
    Human,Mouse,Rat
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Form
    Liquid
  • Clonality No.
    -
  • SwissProt ID
    P78536
  • Research Field
    Neuroscience
  • Gene ID
    6868
  • Modification
    Unmodified
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