Cat.#： 382214
Alternative Names： ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated
Application： WB,ICC/IF,IP,FC
Reactivity： Human,Mouse,Rat
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Quantity： - + （库存件）
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Doc. Data Sheet
Product Details
  • Product Categories
    Primary antibody
  • Product Name
    ATM Rabbit pAb
  • Background
    The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability.
  • Alternative Names
    ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated
  • Immunogen
    A synthesized peptide derived from human ATM
  • Buffer System
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Dilution Ratio
    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/80 FC: 1/50-1/100
  • Molecular Weight
    Calculated MW: 351 kDa; Observed MW: 351 kDa
  • Clonality
    Polyclonal Antibody
  • Gene Name
    ATM
  • Conjugation
    Unconjugated
  • Isotype
    IgG
  • Host
    Rabbit
  • Application
    WB,ICC/IF,IP,FC
  • Purification
    Affinity Chromatography
  • Reactivity
    Human,Mouse,Rat
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Form
    Liquid
  • Clonality No.
    -
  • SwissProt ID
    Q13315
  • Research Field
    Epigenetics and Nuclear Signaling
  • Gene ID
    472
  • Modification
    Unmodified
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