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Product Categories
Primary antibody
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Product Name
Estrogen Receptor alpha (6F11) Mouse mAb
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Background
ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.
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Alternative Names
ESR1; Era; Eralpha; Estrogen receptor; Estradiol receptor; ER-alpha; Estrogen receptor 1; NR3A1; ER; ESR; ESRA; Estrogen receptor alpha
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Immunogen
Purified recombinant human Estrogen Receptor αMMP-2 protein expressed in E.coli.
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 66 kDa; Observed MW: 66 kDa
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Clonality
Monoclonal Antibody
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Gene Name
ESR1
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Conjugation
Unconjugated
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Isotype
IgG2b
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Host
Mouse
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Application
WB
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Purification
Affinity Purified
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Reactivity
Transfected
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Form
Liquid
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Clonality No.
6F11-C3-G6
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SwissProt ID
P03372
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Research Field
Signal Transduction
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Gene ID
2099
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Modification
Unmodified