Cat.#： 201258
Alternative Names： NNE; PPH; MPB1; ENO1L1; HEL-S-17
Application： WB
Reactivity： Human,Mouse,Rat,Monkey
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Doc. Data Sheet
Product Details
  • Product Categories
    Primary antibody
  • Product Name
    ENO1 (3F7) Mouse mAb
  • Background
    Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.MiscellaneousUsed as a diagnostic marker for many tumors and, in the heterodimeric form, alpha/gamma, as a marker for hypoxic brain injury after cardiac arrest. Also marker for endometriosis. Antibodies against alpha-enolase are present in sera from patients with cancer-associated retinopathy syndrome (CAR), a progressive blinding disease which occurs in the presence of systemic tumor growth, primarily small-cell carcinoma of the lung and other malignancies. Is identified as an autoantigen in Hashimoto encephalopathy (HE) a rare autoimmune disease associated with Hashimoto thyroiditis (HT). HT is a disorder in which destructive processes overcome the potential capacity of thyroid replacement leading to hypothyroidism.
  • Alternative Names
    NNE; PPH; MPB1; ENO1L1; HEL-S-17
  • Immunogen
    Purified recombinant human Enolase-1 protein fragments expressed in E.coli.
  • Buffer System
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
  • Dilution Ratio
    WB: 1/500-1/1000
  • Molecular Weight
    Calculated MW: 47 kDa; Observed MW: 47 kDa
  • Clonality
    Monoclonal Antibody
  • Gene Name
    ENO1
  • Conjugation
    Unconjugated
  • Isotype
    IgG1
  • Host
    Mouse
  • Application
    WB
  • Purification
    Affinity Purified
  • Reactivity
    Human,Mouse,Rat,Monkey
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Form
    Liquid
  • Clonality No.
    3F7-B12-D10
  • SwissProt ID
    P06733
  • Research Field
    Signal Transduction
  • Gene ID
    2023
  • Modification
    Unmodified
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