Cat.#: 240125
Alternative Names: APG3; APG3L; PC3-96; APG3-LIKE
Application: WB,IHC-P
Reactivity: Human,Mouse,Rat
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Product Details
  • Product Categories
    KO/KD validated
  • Product Name
    [KO] ATG3 Mouse mAb
  • Background
    E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). Catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.
  • Alternative Names
    APG3; APG3L; PC3-96; APG3-LIKE
  • Immunogen
    Full length human recombinant protein of human ATG3 produced in 293T cell.
  • Buffer System
    Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100
  • Molecular Weight
    Calculated MW: 36 kDa; Observed MW: 42 kDa
  • Gene Name
    ATG3
  • Host
    Mouse
  • Reactivity
    Human,Mouse,Rat
  • Conjugation
    Unconjugated
  • Application
    WB,IHC-P
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • SwissProt ID
    Q9NT62
  • Purification
    Affinity Purified
  • Clonality No.
    4F6
  • Clonality
    Monoclonal Antibody
  • Isotype
    IgG1
  • Form
    Liquid
  • Research Field
    Cell Biology
  • Gene ID
    64422
  • Modification
    Unmodified
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