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Product Categories
Antibody Pair
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Product Name
Kit ligand Rat mAb, capture
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Background
Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1.
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Alternative Names
SF; SCF; MGF; FPH2; KL-1; Kitl; Kit ligand
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Immunogen
A synthesized peptide derived from soluble human Kit ligand
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Concentration
1 mg/ml
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Buffer System
Liquid in PBS containing 0.09% sodium azide as a preservative.
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Dilution Ratio
ELISA: 1/1000
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Molecular Weight
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Clonality
Monoclonal Antibody
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Gene Name
KITLG
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Conjugation
Unconjugated
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Isotype
IgG2a
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Host
Rat
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Application
ELISA
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Purification
Affinity Purified
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Reactivity
Human
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Form
Liquid
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Clonality No.
17E8
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SwissProt ID
P21583
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Research Field
Immunology
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Gene ID
4254
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Modification
Unmodified