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Product Categories
Antibody Pair
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Product Name
Endostatin Mouse mAb, unconjugated, detector
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Background
This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Alternative Names
KS; Endostatin; KNO; KNO1
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Immunogen
A synthesized peptide derived from endostatin
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Buffer System
Liquid in PBS containing 0.09% sodium azide as a preservative.
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Dilution Ratio
ELISA: 1/1000
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Molecular Weight
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Clonality
Monoclonal Antibody
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Gene Name
COL18A1
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Conjugation
Unconjugated
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Isotype
IgG2a
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Host
Mouse
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Application
ELISA
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Purification
Affinity Purified
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Reactivity
Human
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Form
Liquid
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Clonality No.
5E3
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SwissProt ID
P39060
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Research Field
Cardiovascular
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Gene ID
80781
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Modification
Unmodified