-
Product Categories
Loading Control antibody
-
Product Name
Histone H3 Rabbit pAb (HRP)
-
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.MiscellaneousThis histone is only present in mammals and is enriched in acetylation of Lys-15 and dimethylation of Lys-10 (H3K9me2).
-
Alternative Names
H3 histone; HIST1H3A; Histone cluster 1; H3a
-
Immunogen
A synthetic peptide corresponding to the carboxy terminus of the human histone H3 protein.
-
Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
-
Dilution Ratio
WB: 1/5000-1/10000
-
Molecular Weight
Calculated MW: 15 kDa; Observed MW: 15 kDa
-
Clonality
Polyclonal Antibody
-
Gene Name
H3C1
-
Conjugation
HRP
-
Isotype
IgG
-
Host
Rabbit
-
Application
WB
-
Purification
Affinity Purified
-
Reactivity
Human,Mouse,Rat
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
Form
Liquid
-
Clonality No.
-
-
SwissProt ID
P68431
-
Research Field
Epigenetics and Nuclear Signaling
-
Gene ID
8350
-
Modification
Unmodified