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Product Categories
Recombinant Rabbit Monoclonal antibody
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Product Name
Caspase 9 Rabbit mAb
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Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
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Alternative Names
CASP 9; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6; Caspase-9 subunit p35; Caspase-9 subunit p10; CASP9; MCH6
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Immunogen
Recombinant protein of mouse Caspase-9
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Dilution Ratio
WB: 1/500-1/1000 IP: 1/20
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Molecular Weight
Calculated MW: 50 kDa; Observed MW: 50 kDa
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Gene Name
Casp9
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Host
Rabbit
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Reactivity
Mouse,Rat
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Conjugation
Unconjugated
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Application
WB,IP
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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SwissProt ID
Q8C3Q9
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Purification
Affinity Purified
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Clonality No.
R04-8I4
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Clonality
Monoclonal Antibody
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Isotype
IgG
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Form
Liquid
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Research Field
Cell Biology
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Gene ID
12371
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Modification
Unmodified