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Product Categories
Recombinant Rabbit Monoclonal antibody
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Product Name
CDKN2A/p16INK4a Rabbit mAb
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Background
Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.CautionThe proteins described here are encoded by the gene CDKN2A, but are completely unrelated in terms of sequence and function to tumor suppressor ARF (AC Q64364) which is encoded by the same gene.
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Alternative Names
Cdkn2a;P16ink4a;Cyclin-dependent kinase 4 inhibitor A (CDK4I);p16-INK4a ;p16-INK4
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Immunogen
Recombinant protein of mouse CDKN2A/p16INK4a
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
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Molecular Weight
Calculated MW: 18 kDa; Observed MW: 18 kDa
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Gene Name
Cdkn2A
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Host
Rabbit
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Reactivity
Mouse,Rat
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Conjugation
Unconjugated
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Application
WB,ICC/IF,IP
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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SwissProt ID
P51480
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Purification
Affinity Purified
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Clonality No.
R07-2K1
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Clonality
Monoclonal Antibody
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Isotype
IgG
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Form
Liquid
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Research Field
Cell Biology
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Gene ID
12578
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Modification
Unmodified