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Product Categories
Recombinant Rabbit Monoclonal antibody
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Product Name
Chk2 Rabbit mAb
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Background
These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.
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Alternative Names
CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2
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Immunogen
Recombinant protein of human Chk2
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
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Molecular Weight
Calculated MW: 61 kDa; Observed MW: 61 kDa
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Gene Name
CHEK2
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Host
Rabbit
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Reactivity
Human
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Conjugation
Unconjugated
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Application
WB,ICC/IF,IP
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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SwissProt ID
O96017
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Purification
Affinity Purified
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Clonality No.
R04-8E5
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Clonality
Monoclonal Antibody
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Isotype
IgG
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Form
Liquid
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Research Field
Epigenetics and Nuclear Signaling
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Gene ID
11200
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Modification
Unmodified