Cat.#: R23928
Alternative Names: STP; CIP4; HSTP; STOT; TRIP-10
Application: WB
Reactivity: Human,Mouse,Rat
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Doc. Data Sheet
Product Details
  • Product Categories
    Recombinant Rabbit Monoclonal antibody
  • Product Name
    CIP4 Rabbit mAb
  • Background
    Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling . Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
  • Alternative Names
    STP; CIP4; HSTP; STOT; TRIP-10
  • Immunogen
    A synthetic peptide of human Cip4
  • Buffer System
    50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
  • Dilution Ratio
    WB: 1/500-1/1000
  • Molecular Weight
    Calculated MW: 68 kDa; Observed MW: 80 kDa
  • Gene Name
    TRIP10
  • Host
    Rabbit
  • Reactivity
    Human,Mouse,Rat
  • Conjugation
    Unconjugated
  • Application
    WB
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • SwissProt ID
    Q15642
  • Purification
    Affinity Purified
  • Clonality No.
    R01-6B7
  • Clonality
    Monoclonal Antibody
  • Isotype
    IgG
  • Form
    Liquid
  • Research Field
    Cell Biology
  • Gene ID
    9322
  • Modification
    Unmodified
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