-
Product Categories
Recombinant Rabbit Monoclonal antibody
-
Product Name
CIP4 Rabbit mAb
-
Background
Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling . Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
-
Alternative Names
STP; CIP4; HSTP; STOT; TRIP-10
-
Immunogen
A synthetic peptide of human Cip4
-
Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
-
Molecular Weight
Calculated MW: 68 kDa; Observed MW: 80 kDa
-
Gene Name
TRIP10
-
Host
Rabbit
-
Reactivity
Human,Mouse
-
Conjugation
Unconjugated
-
Application
WB,IHC-P
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
SwissProt ID
Q15642
-
Purification
Affinity Purified
-
Clonality No.
R02-7A4
-
Clonality
Monoclonal Antibody
-
Isotype
IgG
-
Form
Liquid
-
Research Field
Cell Biology
-
Gene ID
9322
-
Modification
Unmodified