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Product Categories
Recombinant Rabbit Monoclonal antibody
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Product Name
CIRBP Rabbit mAb
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Background
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor . Promotes assembly of stress granules (SGs), when overexpressed.
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Alternative Names
CIRP
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Immunogen
Recombinant protein of human CIRBP
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
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Molecular Weight
Calculated MW: 19 kDa; Observed MW: 19 kDa
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Gene Name
CIRBP
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Host
Rabbit
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Reactivity
Human
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Conjugation
Unconjugated
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Application
WB,IHC-P,IP
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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SwissProt ID
Q14011
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Purification
Affinity Purified
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Clonality No.
R01-4B2
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Clonality
Monoclonal Antibody
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Isotype
IgG
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Form
Liquid
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Research Field
Epigenetics and Nuclear Signaling
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Gene ID
1153
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Modification
Unmodified