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Product Categories
Recombinant Rabbit Monoclonal antibody
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Product Name
5T4 Rabbit mAb
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Background
5T4 is a 72 kDa transmembrane glycoprotein that exhibits restricted expression in human and mouse adult tissues, is upregulated on many carcinomas and tumour expression correlates with poorer clinical outcome in ovarian, gastric and colorectal cancers. mES cells lack cell surface expression of the 5T4 antigen, and both protein and mRNA are rapidly upregulated following induction of differentiation. This proteins expression correlates with downregulation of OCT-4 and Tra-1–60.
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Alternative Names
5T4; 5T4AG; M6P1; TPBG; 5T4 oncofetal antigen; Trophoblast glycoprotein
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Immunogen
A synthetic peptide of human 5T4
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Dilution Ratio
WB: 1/500-1/1000 IP: 1/20
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Molecular Weight
Calculated MW: 46 kDa; Observed MW: 78 kDa
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Gene Name
TPBG
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Conjugation
Unconjugated
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Application
WB,IP
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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SwissProt ID
Q13641
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Purification
Affinity Purified
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Clonality No.
R05-3A0
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Clonality
Monoclonal Antibody
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Isotype
IgG
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Form
Liquid
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Research Field
Stem Cells
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Gene ID
7162
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Modification
Unmodified