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Product Categories
Recombinant Rabbit Monoclonal antibody
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Product Name
Caspase 1 Rabbit mAb
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Background
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
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Alternative Names
CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45
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Immunogen
Recombinant protein of human Caspase-1
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Dilution Ratio
WB: 1/500-1/1000 IP: 1/20
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Molecular Weight
Calculated MW: 45 kDa; Observed MW: 45,20 kDa
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Gene Name
CASP1
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Host
Rabbit
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Reactivity
Human
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Conjugation
Unconjugated
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Application
WB,IP
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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SwissProt ID
P29466
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Purification
Affinity Purified
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Clonality No.
R05-7H1
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Clonality
Monoclonal Antibody
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Isotype
IgG
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Form
Liquid
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Research Field
Cell Biology
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Gene ID
834
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Modification
Unmodified