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Product Categories
Primary antibody
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Product Name
Alpha-2-Macroglobulin Rabbit mAb
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Background
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
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Alternative Names
Alpha-2-Macroglobulin; A2m; Alpha 2M; Alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; FWP007; S863 7
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Immunogen
A synthesized peptide derived from human A2M
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 163 kDa; Observed MW: 163 kDa
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Gene Name
A2M
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Host
Rabbit
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Reactivity
Human
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Conjugation
Unconjugated
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Application
WB,IHC-P
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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SwissProt ID
P01023
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Purification
Affinity Chromatography
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Clonality No.
R02-9D9
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Clonality
Monoclonal Antibody
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Isotype
IgG
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Form
Liquid
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Research Field
Cardiovascular
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Gene ID
2
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Modification
Unmodified