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Product Categories
Recombinant Rabbit Monoclonal antibody
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Product Name
Complement C9 Rabbit mAb
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Background
C9 is synthesised in the liver and monocytes, and is a plasma protein consisting of a single polypeptide chain of molecular weight 71kDa. Normal plasma concentration is 60mg/L. C9 forms part of the membrane attack complex (MAC) the cytolytic terminal complex of the complement pathways. C9 binds to the membrane associated C5b-8, binding of C9 to C5b-8 leads to the circular polymerisation of 12-18 C9 molecules. This is the basis of the hydrophilic, protein-walled, trans-membrane channel formed by the MAC, which leads to cell lysis and destruction.
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Alternative Names
Complement component C9; Comple Complement component C9bment component C9a
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Immunogen
A synthesized peptide derived from human C9
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/50
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Molecular Weight
Calculated MW: 63 kDa; Observed MW: 70 kDa
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Gene Name
C9
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Host
Rabbit
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Reactivity
Human
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Conjugation
Unconjugated
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Application
WB,IHC-P,IP
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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SwissProt ID
P02748
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Purification
Affinity Chromatography
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Clonality No.
R04-1H2
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Clonality
Monoclonal Antibody
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Isotype
IgG
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Form
Liquid
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Research Field
Immunology
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Gene ID
735
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Modification
Unmodified