ATG4A Rabbit mAb - Chengdu Zhengneng Biotechnology Co., Ltd

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Cat.#： R382041

Alternative Names： ATG4A; APG4A; AUTL2; Cysteine protease ATG4A; AUT-like 2 cysteine endopeptidase; Autophagin-2; Autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; hAPG4A

Application： WB,IHC-P,IP

Reactivity： Human,Mouse,Rat

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Recombinant Rabbit Monoclonal antibody
Product Name

ATG4A Rabbit mAb
Background

The cysteine protease Atg4 is pivotal to autophagosome membrane generation and regulation. Atg4 primes the Atg8 homologue for lipidation by cleaving its carboxy terminus and exposing its glycine residue for E1-like enzyme Atg7. The Atg8 homologue is transferred to the E2-like enzyme Atg3 before forming the Atg8-PE conjugate. During later stages of autophagy, Atg4 can reverse this lipidation event by cleaving PE, thereby recycling the Atg8 homologue.
Alternative Names

ATG4A; APG4A; AUTL2; Cysteine protease ATG4A; AUT-like 2 cysteine endopeptidase; Autophagin-2; Autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; hAPG4A
Immunogen

A synthesized peptide derived from human Atg4A
Buffer System

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/50
Molecular Weight

Calculated MW: 45 kDa; Observed MW: 45 kDa
Gene Name

ATG4A
Host

Rabbit
Reactivity

Human,Mouse,Rat
Conjugation

Unconjugated
Application

WB,IHC-P,IP
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
SwissProt ID

Q8WYN0
Purification

Affinity Chromatography
Clonality No.

R07-3J5
Clonality

Monoclonal Antibody
Isotype

IgG
Form

Liquid
Research Field

Cell Biology
Gene ID

115201
Modification

Unmodified