Cat.#： R380926
Alternative Names： ARB1; ARR1; ARRB1; ARRB1_HUMAN; Arrestin 2; Arrestin beta 1; Arrestin beta-1; Beta-arrestin-1.
Application： WB,IHC-P,ICC/IF,FC
Reactivity： Human,Mouse,Rat
Price：
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Quantity： - + （库存件）
Availability：3-4 working days Contact the local distributor
Doc. Data Sheet
Product Details
  • Product Categories
    Recombinant Rabbit Monoclonal antibody
  • Product Name
    ARRB1 Rabbit mAb
  • Background
    Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]
  • Alternative Names
    ARB1; ARR1; ARRB1; ARRB1_HUMAN; Arrestin 2; Arrestin beta 1; Arrestin beta-1; Beta-arrestin-1.
  • Immunogen
    A synthesized peptide derived from human ARRB1
  • Buffer System
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
  • Molecular Weight
    Calculated MW: 47 kDa; Observed MW: 50 kDa
  • Gene Name
    ARRB1
  • Host
    Rabbit
  • Reactivity
    Human,Mouse,Rat
  • Conjugation
    Unconjugated
  • Application
    WB,IHC-P,ICC/IF,FC
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • SwissProt ID
    P49407
  • Purification
    Affinity Chromatography
  • Clonality No.
    R08-5I9
  • Clonality
    Monoclonal Antibody
  • Isotype
    IgG
  • Form
    Liquid
  • Research Field
    Signal Transduction
  • Gene ID
    408
  • Modification
    Unmodified
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