-
Product Categories
Primary antibody
-
Product Name
5T4 Rabbit mAb
-
Background
5T4 is a 72 kDa transmembrane glycoprotein that exhibits restricted expression in human and mouse adult tissues, is upregulated on many carcinomas and tumour expression correlates with poorer clinical outcome in ovarian, gastric and colorectal cancers. mES cells lack cell surface expression of the 5T4 antigen, and both protein and mRNA are rapidly upregulated following induction of differentiation. This proteins expression correlates with downregulation of OCT-4 and Tra-1–60.
-
Alternative Names
5T4; 5T4AG; M6P1; TPBG; 5T4 oncofetal antigen; Trophoblast glycoprotein
-
Immunogen
A synthesized peptide derived from human 5T4
-
Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
-
Molecular Weight
Calculated MW: 46 kDa; Observed MW: 80 kDa
-
Gene Name
TPBG
-
Host
Rabbit
-
Reactivity
Human
-
Conjugation
Unconjugated
-
Application
WB,IHC-P
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
SwissProt ID
Q13641
-
Purification
Affinity Chromatography
-
Clonality No.
R09-1G5
-
Clonality
Monoclonal Antibody
-
Isotype
IgG
-
Form
Liquid
-
Research Field
Stem Cells
-
Gene ID
7162
-
Modification
Unmodified