Cat.#: R381168
Alternative Names: 5T4; 5T4AG; M6P1; TPBG; 5T4 oncofetal antigen; Trophoblast glycoprotein
Application: WB,IHC-P
Reactivity: Human
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Doc. Data Sheet
Product Details
  • Product Categories
    Recombinant Rabbit Monoclonal antibody
  • Product Name
    5T4 Rabbit mAb
  • Background
    5T4 is a 72 kDa transmembrane glycoprotein that exhibits restricted expression in human and mouse adult tissues, is upregulated on many carcinomas and tumour expression correlates with poorer clinical outcome in ovarian, gastric and colorectal cancers. mES cells lack cell surface expression of the 5T4 antigen, and both protein and mRNA are rapidly upregulated following induction of differentiation. This proteins expression correlates with downregulation of OCT-4 and Tra-1–60.
  • Alternative Names
    5T4; 5T4AG; M6P1; TPBG; 5T4 oncofetal antigen; Trophoblast glycoprotein
  • Immunogen
    A synthesized peptide derived from human 5T4
  • Buffer System
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100
  • Molecular Weight
    Calculated MW: 46 kDa; Observed MW: 80 kDa
  • Gene Name
    TPBG
  • Host
    Rabbit
  • Reactivity
    Human
  • Conjugation
    Unconjugated
  • Application
    WB,IHC-P
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • SwissProt ID
    Q13641
  • Purification
    Affinity Chromatography
  • Clonality No.
    R09-1G5
  • Clonality
    Monoclonal Antibody
  • Isotype
    IgG
  • Form
    Liquid
  • Research Field
    Stem Cells
  • Gene ID
    7162
  • Modification
    Unmodified
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