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Product Categories
Primary antibody
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Product Name
14-3-3 sigma Rabbit mAb
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Background
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
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Alternative Names
SFN; HME1; 14-3-3 protein sigma; Epithelial cell marker protein 1; Stratifin
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Immunogen
A synthesized peptide derived from human 14-3-3 sigma
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 28 kDa; Observed MW: 28 kDa
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Gene Name
SFN
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Host
Rabbit
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Reactivity
Human,Rat
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Conjugation
Unconjugated
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Application
WB,IHC-P
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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SwissProt ID
P31947
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Purification
Affinity Chromatography
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Clonality No.
R01-5C8
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Clonality
Monoclonal Antibody
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Isotype
IgG
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Form
Liquid
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Research Field
Neuroscience
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Gene ID
2810
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Modification
Unmodified