Cat.#: R381693
Alternative Names: Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin
Application: WB,IHC-P,ICC/IF,FC,IP
Reactivity: Human
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Doc. Data Sheet
Product Details
  • Product Categories
    Recombinant Rabbit Monoclonal antibody
  • Product Name
    alpha 1 Fetoprotein Rabbit mAb
  • Background
    Alpha-fetoprotein (AFP) is a 65 kDa glycoprotein found in the mammalian fetal liver, yolk sac, and GI tract. In normal adult cells, p53 binds to the repressor region of the AFP gene, thereby blocking transcription. Mutations in both p53 and β-catenin are associated with aberrant expression of AFP. Research studies have shown that elevated serum AFP levels are predictive of hepatocellular carcinoma .
  • Alternative Names
    Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin
  • Immunogen
    A synthesized peptide derived from human AFP
  • Buffer System
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
  • Molecular Weight
    Calculated MW: 69 kDa; Observed MW: 69 kDa
  • Gene Name
    AFP
  • Host
    Rabbit
  • Reactivity
    Human
  • Conjugation
    Unconjugated
  • Application
    WB,IHC-P,ICC/IF,FC,IP
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • SwissProt ID
    P02771
  • Purification
    Affinity Chromatography
  • Clonality No.
    R04-3C6
  • Clonality
    Monoclonal Antibody
  • Isotype
    IgG
  • Form
    Liquid
  • Research Field
    Cancer
  • Gene ID
    174
  • Modification
    Unmodified
Verification details
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