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Product Categories
Recombinant Rabbit Monoclonal antibody
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Product Name
alpha 1 Fetoprotein Rabbit mAb
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Background
Alpha-fetoprotein (AFP) is a 65 kDa glycoprotein found in the mammalian fetal liver, yolk sac, and GI tract. In normal adult cells, p53 binds to the repressor region of the AFP gene, thereby blocking transcription. Mutations in both p53 and β-catenin are associated with aberrant expression of AFP. Research studies have shown that elevated serum AFP levels are predictive of hepatocellular carcinoma .
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Alternative Names
Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin
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Immunogen
A synthesized peptide derived from human AFP
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 69 kDa; Observed MW: 69 kDa
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Gene Name
AFP
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Host
Rabbit
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Reactivity
Human
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Conjugation
Unconjugated
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Application
WB,IHC-P,ICC/IF,FC,IP
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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SwissProt ID
P02771
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Purification
Affinity Chromatography
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Clonality No.
R04-3C6
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Clonality
Monoclonal Antibody
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Isotype
IgG
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Form
Liquid
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Research Field
Cancer
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Gene ID
174
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Modification
Unmodified