Cat.#： R382214
Alternative Names： ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated
Application： WB,ICC/IF,FC,IP
Reactivity： Human,Mouse,Rat
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Doc. Data Sheet
Product Details
  • Product Categories
    Recombinant Rabbit Monoclonal antibody
  • Product Name
    ATM Rabbit mAb
  • Background
    The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability.
  • Alternative Names
    ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated
  • Immunogen
    A synthesized peptide derived from human ATM
  • Buffer System
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Dilution Ratio
    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/80 FC: 1/50-1/100
  • Molecular Weight
    Calculated MW: 351 kDa
  • Gene Name
    ATM
  • Host
    Rabbit
  • Reactivity
    Human,Mouse,Rat
  • Conjugation
    Unconjugated
  • Application
    WB,ICC/IF,FC,IP
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • SwissProt ID
    Q13315
  • Purification
    Affinity Chromatography
  • Clonality No.
    R07-5J6
  • Clonality
    Monoclonal Antibody
  • Isotype
    IgG
  • Form
    Liquid
  • Research Field
    Epigenetics and Nuclear Signaling
  • Gene ID
    472
  • Modification
    Unmodified
Verification details
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