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Product Categories
Primary antibody
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Product Name
Angiopoietin 1 Rabbit pAb
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Background
Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Required for normal angiogenesis and heart development during embryogenesis. After birth, activates or inhibits angiogenesis, depending on the context.
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Alternative Names
ANGPT1; KIAA0003; Angiopoietin-1; ANG-1
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Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human ANGPT1.
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
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Molecular Weight
Calculated MW: 58 kDa; Observed MW: 58 kDa
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Clonality
Polyclonal Antibody
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Gene Name
ANGPT1
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Conjugation
Unconjugated
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Isotype
IgG
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Host
Rabbit
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Application
WB,IHC-P,ELISA
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Purification
Affinity Purified
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Reactivity
Human,Rat
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Form
Liquid
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Clonality No.
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SwissProt ID
Q15389
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Research Field
Cancer
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Gene ID
284
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Modification
Unmodified