Cat.#: 341030
Alternative Names: CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45
Application: WB,IHC-F,IHC-P,ICC/IF,ELISA
Reactivity: Human,Mouse,Rat
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Doc. Data Sheet
Product Details
  • Product Categories
    Primary antibody
  • Product Name
    Cleaved-Caspase 1 Rabbit pAb
  • Background
    Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
  • Alternative Names
    CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45
  • Immunogen
    The antiserum was produced against synthesized peptide derived from human Cleaved-Caspase 1.
  • Buffer System
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
  • Molecular Weight
    Calculated MW: 45 kDa; Observed MW: 25 kDa
  • Clonality
    Polyclonal Antibody
  • Gene Name
    CASP1
  • Conjugation
    Unconjugated
  • Isotype
    IgG
  • Host
    Rabbit
  • Application
    WB,IHC-F,IHC-P,ICC/IF,ELISA
  • Purification
    Affinity Purified
  • Reactivity
    Human,Mouse,Rat
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Form
    Liquid
  • Clonality No.
    -
  • SwissProt ID
    P29466
  • Research Field
    Cell Biology
  • Gene ID
    834
  • Modification
    Cleaved
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