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Product Categories
Primary antibody
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Product Name
Cytochrome P450 11B2 Rabbit pAb
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Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.
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Alternative Names
CPN2; ALDOS; CYP11B; CYP11BL; CYPXIB2; P450C18; P-450C18; P450aldo
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Immunogen
Synthetic peptide of human CYP11B2
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Buffer System
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 58 kDa; Observed MW: 58 kDa
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Clonality
Polyclonal Antibody
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Gene Name
CYP11B2
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Conjugation
Unconjugated
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Isotype
IgG
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Host
Rabbit
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Application
WB,IHC-P
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Purification
Affinity Purified
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Reactivity
Human
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Form
Liquid
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Clonality No.
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SwissProt ID
P19099
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Research Field
Cardiovascular
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Gene ID
1585
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Modification
Unmodified