alpha Smooth Muscle Actin (3G2) Mouse mAb - Primary Antibodies - Chengdu Zhengneng Biotechnology Co., Ltd

Cat.#： 250104

Alternative Names： ACTA2; ACTSA; ACTVS; GIG46; Actin; aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein; α-SMA

Application： WB,IHC-F,IHC-P,ICC/IF

Reactivity： Human,Mouse,Rat

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Primary antibody
Product Name

alpha Smooth Muscle Actin (3G2) Mouse mAb
Background

Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
Alternative Names

ACTA2; ACTSA; ACTVS; GIG46; Actin; aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein; α-SMA
Immunogen

Synthetic Peptide of α-SMA
Buffer System

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Molecular Weight

Calculated MW: 42 kDa; Observed MW: 42 kDa
Clonality

Monoclonal Antibody
Gene Name

ACTA2
Conjugation

Unconjugated
Isotype

IgG1
Host

Mouse
Application

WB,IHC-F,IHC-P,ICC/IF
Purification

Affinity Purified
Reactivity

Human,Mouse,Rat
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Form

Liquid
Clonality No.

3G2-2G9-4G5
SwissProt ID

P62736
Research Field

Signal Transduction
Gene ID

59
Modification

Unmodified