Cat.#: 250104
Alternative Names: ACTA2; ACTSA; ACTVS; GIG46; Actin; aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein; α-SMA
Application: WB,IHC-F,IHC-P,ICC/IF
Reactivity: Human,Mouse,Rat
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Doc. Data Sheet
Product Details
  • Product Categories
    Primary antibody
  • Product Name
    alpha Smooth Muscle Actin (3G2) Mouse mAb
  • Background
    Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
  • Alternative Names
    ACTA2; ACTSA; ACTVS; GIG46; Actin; aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein; α-SMA
  • Immunogen
    Synthetic Peptide of α-SMA
  • Buffer System
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
  • Molecular Weight
    Calculated MW: 42 kDa; Observed MW: 42 kDa
  • Clonality
    Monoclonal Antibody
  • Gene Name
    ACTA2
  • Conjugation
    Unconjugated
  • Isotype
    IgG1
  • Host
    Mouse
  • Application
    WB,IHC-F,IHC-P,ICC/IF
  • Purification
    Affinity Purified
  • Reactivity
    Human,Mouse,Rat
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Form
    Liquid
  • Clonality No.
    3G2-2G9-4G5
  • SwissProt ID
    P62736
  • Research Field
    Signal Transduction
  • Gene ID
    59
  • Modification
    Unmodified
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