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Product Categories
Primary antibody
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Product Name
ABCB5 (8D2) Mouse mAb
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Background
Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.
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Alternative Names
ABCB5 P-gp; ATP binding cassette sub family B (MDR/TAP) member 5; P glycoprotein ABCB5
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Immunogen
Synthetic Peptide of ABCB5
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 139 kDa; Observed MW: 90 kDa
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Clonality
Monoclonal Antibody
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Gene Name
ABCB5
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Conjugation
Unconjugated
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Isotype
IgG1
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Host
Mouse
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Application
WB,ICC/IF
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Purification
Affinity Purified
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Reactivity
Human
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Form
Liquid
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Clonality No.
8D2-2B8-4E8
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SwissProt ID
Q2M3G0
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Research Field
Signal Transduction
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Gene ID
340273
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Modification
Unmodified