Cat.#： 250015
Alternative Names： GP180; L CA; CD45 antigen
Application： WB,IHC-F,IHC-P,ICC/IF
Reactivity： Human
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Doc. Data Sheet
Product Details
  • Product Categories
    Primary antibody
  • Product Name
    CD45 (8C1) Mouse mAb
  • Background
    Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.
  • Alternative Names
    GP180; L CA; CD45 antigen
  • Immunogen
    Synthetic Peptide of CD45
  • Buffer System
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
  • Molecular Weight
    Calculated MW: 145 kDa; Observed MW: 145 kDa
  • Clonality
    Monoclonal Antibody
  • Gene Name
    Ptprc
  • Conjugation
    Unconjugated
  • Isotype
    IgG1
  • Host
    Mouse
  • Application
    WB,IHC-F,IHC-P,ICC/IF
  • Purification
    Affinity Purified
  • Reactivity
    Human
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Form
    Liquid
  • Clonality No.
    8C1-9B8-2H1
  • SwissProt ID
    P08575
  • Research Field
    Immunology
  • Gene ID
    19264
  • Modification
    Unmodified
Verification details
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