Bak Rabbit pAb - Primary Antibodies - Chengdu Zhengneng Biotechnology Co., Ltd

Cat.#： 380976

Alternative Names： BAK1; BAK; BCL2L7; CDN1; Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7

Application： WB,IHC-P,ICC/IF,IP,FC

Reactivity： Human,Mouse

Price：

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Quantity： - + （库存件）

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Product Details

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Primary antibody
Product Name

Bak Rabbit pAb
Background

Bak is a proapoptotic member of the Bcl-2 family. This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway. Upon apoptotic stimulation, an upstream stimulator like truncated BID (tBID) induces conformational changes in Bak to form oligomer channels in the mitochondrial membrane for cytochrome c release. The release of cytochrome c to the cytosol activates the caspase-9 pathway and eventually leads to cell death.
Alternative Names

BAK1; BAK; BCL2L7; CDN1; Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7
Immunogen

A synthesized peptide derived from human Bak
Buffer System

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Molecular Weight

Calculated MW: 23 kDa; Observed MW: 23 kDa
Clonality

Polyclonal Antibody
Gene Name

BAK1
Conjugation

Unconjugated
Isotype

IgG
Host

Rabbit
Application

WB,IHC-P,ICC/IF,IP,FC
Purification

Affinity Chromatography
Reactivity

Human,Mouse
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Form

Liquid
Clonality No.

-
SwissProt ID

Q16611
Research Field

Cell Biology
Gene ID

578
Modification

Unmodified