Phospho-AKT (Ser473) Rabbit pAb - Primary Antibodies - Chengdu Zhengneng Biotechnology Co., Ltd

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Cat.#： 310021

Alternative Names： AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha

Application： WB,IHC-P

Reactivity： Human,Mouse,Rat

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Primary antibody
Product Name

Phospho-AKT (Ser473) Rabbit pAb
Background

Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.
Alternative Names

AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha
Immunogen

Peptide sequence around phosphorylation site of serine 473 (Q-F-S(p)-Y-S) derived from Human Akt.
Buffer System

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100
Molecular Weight

Calculated MW: 56 kDa; Observed MW: 60 kDa
Clonality

Polyclonal Antibody
Gene Name

AKT1
Conjugation

Unconjugated
Isotype

IgG
Host

Rabbit
Application

WB,IHC-P
Purification

Affinity Chromatography
Reactivity

Human,Mouse,Rat
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Form

Liquid
Clonality No.

-
SwissProt ID

P31749
Research Field

Signal Transduction
Gene ID

207
Modification

Phosphorylated