Cat.#： 310036
Alternative Names： CFL1; CFL; Cofilin-1; 18 kDa phosphoprotein; p18; Cofilin; non-muscle isoform
Application： WB,IHC-P,ICC/IF
Reactivity： Human,Mouse,Rat
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Quantity： - + （库存件）
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Doc. Data Sheet
Product Details
  • Product Categories
    Primary antibody
  • Product Name
    Phospho-Cofilin (Ser3) Rabbit pAb
  • Background
    The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
  • Alternative Names
    CFL1; CFL; Cofilin-1; 18 kDa phosphoprotein; p18; Cofilin; non-muscle isoform
  • Immunogen
    Peptide sequence around phosphorylation site of serine 3 (M-A-S(p)-G-V) derived from Human cofilin.
  • Buffer System
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
  • Molecular Weight
    Calculated MW: 19 kDa; Observed MW: 19 kDa
  • Clonality
    Polyclonal Antibody
  • Gene Name
    CFL1
  • Conjugation
    Unconjugated
  • Isotype
    IgG
  • Host
    Rabbit
  • Application
    WB,IHC-P,ICC/IF
  • Purification
    Affinity Chromatography
  • Reactivity
    Human,Mouse,Rat
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Form
    Liquid
  • Clonality No.
    -
  • SwissProt ID
    P23528
  • Research Field
    Signal Transduction
  • Gene ID
    1072
  • Modification
    Phosphorylated
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