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Product Categories
Primary antibody
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Product Name
Cleaved-Caspase 3 p17 Rabbit pAb
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Background
Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.
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Alternative Names
CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1
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Immunogen
Purified recombinant human Caspase-3 protein fragments expressed in E.coli.
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 32 kDa; Observed MW: 35 kDa
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Clonality
Polyclonal Antibody
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Gene Name
CASP3
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Conjugation
Unconjugated
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Isotype
IgG
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Host
Rabbit
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Application
WB
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Purification
Affinity Purified
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Reactivity
Human,Mouse
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Form
Liquid
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Clonality No.
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SwissProt ID
P42574
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Research Field
Cell Biology
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Gene ID
836
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Modification
Cleaved