Cat.#: 501199
Alternative Names: CD86; CD28LG2; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD antigen CD86
Application: WB,IHC-P,ICC/IF
Reactivity: Human,Mouse,Rat
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Doc. Data Sheet
Product Details
  • Product Categories
    Primary antibody
  • Product Name
    CD86 Rabbit pAb
  • Background
    Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
  • Alternative Names
    CD86; CD28LG2; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD antigen CD86
  • Immunogen
    Recombinant protein of human CD86 (NP_787058.4).
  • Buffer System
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
  • Molecular Weight
    Calculated MW: 38 kDa; Observed MW: 74 kDa
  • Clonality
    Polyclonal Antibody
  • Gene Name
    CD86
  • Conjugation
    Unconjugated
  • Isotype
    IgG
  • Host
    Rabbit
  • Application
    WB,IHC-P,ICC/IF
  • Purification
    Affinity Purified
  • Reactivity
    Human,Mouse,Rat
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Form
    Liquid
  • Clonality No.
    -
  • SwissProt ID
    P42081
  • Research Field
    Immunology
  • Gene ID
    942
  • Modification
    Unmodified
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