Cat.#： R381637
Alternative Names： Ago 2; Argonaute 2; dAgo2; eIF2C 2; hAgo2; PPD
Application： WB,IHC-P,ICC/IF,FC,IP
Reactivity： Human,Mouse,Rat
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Doc. Data Sheet
Product Details
  • Product Categories
    Recombinant Rabbit Monoclonal antibody
  • Product Name
    Argonaute 2 Rabbit mAb
  • Background
    Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). Can also upregulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and upregulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions.
  • Alternative Names
    Ago 2; Argonaute 2; dAgo2; eIF2C 2; hAgo2; PPD
  • Immunogen
    A synthesized peptide derived from human Argonaute 2
  • Buffer System
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Dilution Ratio
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
  • Molecular Weight
    Calculated MW: 97 kDa
  • Gene Name
    AGO2
  • Host
    Rabbit
  • Reactivity
    Human,Mouse,Rat
  • Conjugation
    Unconjugated
  • Application
    WB,IHC-P,ICC/IF,FC,IP
  • Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • SwissProt ID
    Q9UKV8
  • Purification
    Affinity Chromatography
  • Clonality No.
    R09-8P8
  • Clonality
    Monoclonal Antibody
  • Isotype
    IgG
  • Form
    Liquid
  • Research Field
    Epigenetics and Nuclear Signaling
  • Gene ID
    27161
  • Modification
    Unmodified
Verification details
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